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Drostanolone Propionate Profile:
Drostanolone Propionate is a dihydrotestosterone (DHT) derived anabolic steroid. Specifically, Drostanolone is the DHT hormone that has been structurally altered by the addition of a methyl group at the carbon 2 position, This protects the hormone from the metabolic breakdown by the 3-hydroxysteroid dehydrogenase enzyme, which is found in the skeletal muscle. It also greatly increases the hormoneís anabolic nature. This simple structural change is all it takes to create Drostanolone, and from here the small/short Propionate ester is attached in order to control the hormoneís release time.
On a functional basis, Drostanolone is well-known for being one of the only anabolic steroids with strong anti-estrogenic properties. Not only does this steroid carry no estrogenic activity, but it can actually act as an anti-estrogen in the body. This is why it has been effective in the treatment of breast cancer. In fact, the combination of Drostanolone and Nolvadex (Tamoxifen Citrate) has been shown to be far more effective than chemotherapy in the treatment of inoperable breast cancer in postmenopausal women. This also makes it a popular steroid among bodybuilders as it could actually prohibit the need for an anti-estrogen when used in the right cycle. This will also prove advantageous during the cutting phase due to the hardening effects it can provide.
Drostanolone carries relatively low anabolic and androgenic ratings; however, these ratings are somewhat misleading. Itís important to remember DHT, the basis of Drostanolone, is five times more androgenic than testosterone with a much stronger binding affinity to the androgen receptor. This again promotes a harder look and can also enhance fat loss. Most all anabolic steroids are well-noted for enhancing the metabolic rate, but strong androgens have a tendency to directly promote lipolysis.
As an anabolic, Drostanolone isnít well-known for promoting gains in lean muscle mass. It has never been used for muscle wasting in a therapeutic sense and will almost always be found in cutting plans among performance athletes. It can, however, promote significant boosts in strength, which could prove beneficial to an athlete who may not necessarily be looking for raw mass. Without question, the effects of Drostanolone will be displayed in the most efficient way during a cutting cycle. However, for the effects to be truly appreciated the individual will need to be extremely lean. This is why the hormone will most commonly be found at the end of bodybuilding contest prep cycles as the individual should already be fairly lean at this stage. The added Drostanolone will help him lose that last bit of fat that often hangs on for dear life at the end of a cycle. It will also ensure his physique appears as hard as can be. Of course, the anti-estrogenic effect will simply enhance this overall look. For those that are not competitive bodybuilder lean, it is possible that the effects of Drostanolone may not be all that noticeable. The individual who is under 10% body fat should be able to notice some results and produce a harder, dryer look, but much over 10% and the effects may not be all that pronounced.
As a potent androgen, Drostanolone can benefit the athlete looking for a boost in strength. This can be a very beneficial steroid for an athlete who is following a calorie restricted diet in an effort to maintain a specific bodyweight necessary for his pursuit. The individual could easily enjoy moderate increases in strength and a slight improvement in recovery and muscular endurance without unwanted body weight gain.
As a bulking agent, the effects of Drostanolone will prove to be rather week. It is possible the hormone could provide gains in mass similar to Methanolone Enanthate, which wonít be that strong either, if the total dose was high enough. However, the relative gain in size will be very moderate with many anabolic steroids being far more suited for this period of steroidal supplementation. There are those who may wish to include Drostanolone in a bulking plan for its anti-estrogenic and fat loss effects. The latter would ensure they kept their body fat gain minimized during off-season bulking phases, but this isnít reason enough to use it in this phase. Body fat should be controllable without it. As for the anti-estrogenic effects, off-season cycles are normally comprised of large amounts of aromatase activity due to high doses of testosterone. Progesterone activity is also commonly high with the addition of Nandrolone compounds and possible Trenbolone. Consider additional Oxymetholone or Methandienone and this estrogenic activity can become very pronounced. Unfortunately, while possessing anti-estrogenic effects, Drostanolone will not be strong enough to combat this level of estrogenic activity.
The standard Drostanolone dose for adult men will normally fall in the 300-400mg per week range. Normally, this will mean an injection of 100mg every other day for a total of 6-8 weeks. This does not mean 6-8 weeks represents the total cycle, but this is a common time frame for the Drostanolone portion of a stack. Some may alternatively choose to split their dose up into a daily injection schedule, but every other day should suffice.
For female breast cancer treatment, standard dosing calls for 100mg three times per weeks for 8-12 weeks. This will commonly lead to virilization symptoms that could be hard to reverse. However, no one can deny itís still better than cancer. For the female athlete, 50mg per week should be more than enough for a total of 4-6 weeks. Some women may find doses closer to 100mg per week to be justified if they tolerate the hormone well. Doses of this range should be controllable for most women, but individual sensitivity must be kept in mind. Doses that go above the 100mg per week mark or beyond 4-6 weeks of use will more than likely produce virilization symptoms at some level.